Call a POISON CENTER or doctor/physician if you feel unwell. See ‘Data for workers – Inhalation exposure’, with the following additional hazard assessment conclusion in the case of short term: The registered threshold is generally displayed in milligrams per kilogram per bodyweight per day. The Agency thus cannot guarantee the correctness of the information displayed. Registration – indicated if there is at least one dossier registered and disseminated for the substance, how many non-confidential registrations are active and/or inactive and the type of submissions (joint and/or individual). If the test material used is different from the substance being registered an indication will be provided. The BPR regulatory processes identified for the Brief Profile are: Prior Informed Consent (PIC)The PIC Regulation (649/2012) entered into force on 4 July 2014. Though the Agency aims to include as many studies as possible in the Brief Profile endpoint study results/summaries, those studies which do not fit the format or miss crucial information (such as measurement conditions) cannot be processed and therefore will not be included on this page. If no data is available in the registered substance dossiers, this will be indicated by a notification stating ‘Data not provided by the registrant’. Note: Registrants can also select ‘other’ as the test species. This section summarises the values related to phototransformation in soil from all registered dossiers for the substance. For this endpoint registrants do not provide summary data. Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or, The (√- check mark)-icon indicates the classification is defined under. Different classifications can also be due to technical errors made during the notification process. 3 Loss of water from pinacol forms a tertiary carbocation. The quality and correctness of the information remains the responsibility of the data submitter. acetone:[1], As a vicinal-diol, it can rearrange to pinacolone by the pinacol rearrangement, e.g. See information under ‘Applicant’s summary and conclusion – interpretation of results (oral)’. The information has not been reviewed or verified by ECHA or any other authority. OLON Spa, Strada Rivoltana Km 6/7 20053 RODANO Milano Italy, Gas under pressure: refrigerated liquefied gas, Solid: nanomaterial, no surface treatment, Characteristic of sulphur containing compounds, Self-heating substances and mixtures (Cat. EC10 / LC10 or NOEC for microorganisms provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested microorganisms or the no observed effect concentration for microorganisms. For this endpoint registrants do not provide study result data. The REACH regulatory processes identified for the Brief Profile are: Persistent Organic Pollutants (POPs)The POPs Regulation (EU) 2019/1021 entered into force on 15 July 2019, repealing the previous POPs Regulation (EC) No 850/2004. This section summarises the vapour pressure values from all registered dossiers for the substance. Symbol GHS07. This section displays the values related to immunotoxicity from all registered dossiers for the substance. Note: Registrants can also select ‘other’ as the type of density. ECHA’s Guidance Chapter R.12: Use Descriptor system of ECHA’s Guidance on information requirements and chemical safety assessment, ECHA guidance chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment, Guidance on the safe use of the substance, Endocrine disrupter testing in aquatic vertebrates – in vivo, Active/Inactive (pending). Wear protective gloves/protective clothing/eye protection/face protection. The Agency thus cannot guarantee the correctness of the information displayed. Values are generally displayed in milligram per kilo soil (dry weight). The Brief Profile is automatically generated; information requirements under different legislative frameworks may, therefore, not be up-to-date or complete. Note: If the measurement condition (percentage of organic carbon) is not provided by the registrant for adsorption coefficient Kd, the data provided is not processed for the Brief Profile. Registrants can choose the same picklist endpoint conclusions as mentioned under ‘Skin sensitisation’. For sections such as substance use, chemical properties and the classification and labelling of substances, the quantity and quality of the information is the responsibility of manufacturers and importers. Follow specific treatment (see label). All data remain the property of its respective owners.Note that the brief profile is an automatically generated summary and that not all available data may be displayed. If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).Relative density provides substance information on the relatively density (measurement units are not processed for relative density) at a temperature measured in Celsius (°C). Please be aware that as additional data is submitted to ECHA, the brief profile will also be updated to reflect the new situation. Fusce eget lorem sed purus tempus blandit. This information has not been reviewed or verified by ECHA, and may change without prior notice. I agree This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The identification of applicable legislative frameworks is done automatically and without manual verification. Contents. This section summarises the dissociating values from all registered dossiers for the substance. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (in hours, longer prioritised over shorter). Data generally displayed in milligrams per kilogram bodyweight per day. More information on CLH can be found here. Welcome to the ECHA website. See ‘Summary effect on fertility oral route’, except: This section displays the values related to neurotoxicity from all registered dossiers for the substance. test not applicable because organic peroxide. Examples include recommended measures on fire-fighting, transport, recycling and disposal. This section summarises the values related to toxicity to soil microorganisms from all registered dossiers for the substance. It is possible that the harmonisation is introduced through an amendment to the CLP Regulation. Values are generally displayed in milligram per kilo soil (dry weight). If so, the data provided is not processed for the Brief Profile. Bioaccumulation Factor (terrestrial species) L/kg ww provides substance information on the substance’s terrestrial bioaccumulative properties measured in litre per kilogram (wet weight). This section summarises the values related to the screening tests for biodegradation in water from all registered dossiers for the substance. 98. g/mol The CoRAP list includes substances that could pose a risk to human health or the environment and whose (potentially hazardous) properties are to be evaluated by the Member States in the next three years. EC/LC50 for freshwater plants provides substance information on the substance’s effect concentration or lethal concentration for 50% of the freshwater plants in the test, generally displayed in milligram per litre. e(−) as an electron donor in organic solvents was studied. Inhalation exposure provides information on the substance’s hazard assessment conclusions regarding inhalation exposure. Please see Registrants/Suppliers details. The percentage is based on the count of values provided. The Restriction list describes the conditions for the manufacture, placing on the market or use of certain substances, either on their own or in mixtures or articles. Hazard Statements: For example, substance impurities can constitute a valid reason for a different classification of the substance. If a threshold is derived, the type of hazard assessment conclusion is displayed and the registered threshold is reported in (nano/micro/milli)gram per cubic metre. EC/LC50 for freshwater sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the freshwater sediment, generally displayed in milligrams per kilogram sediment (dry weight). pH provides substance information on the substance’s acidity level measured in pH at a temperature measured in °C and a concentration measured in (milli)grams per litre. Melting point. Annex V – indicates if the substance is prohibited from export. Autoflammability / Self-ignition provides substance information on the substance’s self-ignition temperature in °C  at a pressure measured in Pascal. Kd provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon. Units and data are normalised when possible and therefore the unit of measure/order of magnitude in the Brief Profile data may not correspond exactly to the one in the registered dossier. This website uses cookies to ensure you get the best experience on our websites. The information provided in the free-text fields is not published in the Brief Profiles. Suspendisse porttitor leo quis purus porttitor posuere sit amet sit amet nunc. ECHA has no public registered data on the use of this substance in activities or processes at the workplace. This site is not fully supported in Internet Explorer 7 (and earlier versions). Take off contaminated clothing and wash before reuse. Please see the registered dossiers for substance information for the following endpoints: The ’Substance identity’ section links substance identification information from all databases that are maintained by ECHA. Processable data for summary is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor.

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